Article
P pili in uropathogenic E. coli are composite fibres with distinct fibrillar adhesive tips.
Nature - 19 Mar 1992
Kuehn M J, Heuser J, Normark S, Hultgren S J
Abstract excerpt
Escherichia coli is a frequent cause of several common bacterial infections in humans and animals, including urinary tract infections, bacteraemia and bacteria-related diarrhoea and is also the main cause of neonatal meningitis. Microbial attachment to surfaces is a key event in colonization and infection and results mainly from a stereochemical fit between microbial adhesins and complementary receptors on host...
Topics
- Adhesins, Escherichia coli
- Bacterial Outer Membrane Proteins
- Carbohydrate Sequence
- Cloning, Molecular
- Epithelium
- Escherichia coli
- Fimbriae, Bacterial
- Microscopy, Electron
- Molecular Sequence Data
- Mutation
- Operon
