Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Non-canonical roles for Yorkie and Drosophila Inhibitor of Apoptosis 1 in epithelial tube size control.

PloS one - 1 Jan 2014

Robbins Renée M, Gbur Samantha C, Beitel Greg J

Abstract excerpt

Precise control of epithelial tube size is critical for organ function, yet the molecular mechanisms remain poorly understood. Here, we examine the roles of cell growth and a highly conserved organ growth regulatory pathway in controlling the dimensions of the Drosophila tracheal (airway) system, a well-characterized system for investigating epithelial tube morphogenesis. We find that tracheal tube-size is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epithelium
Share to Caspases
Share to Cell Shape

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Inhibitor of Apoptosis Proteins

Share to Organogenesis

Share to Proto-Oncogene Proteins pp60(c-src)

Share to Trachea

Share to YAP-Signaling Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 25036253
DOI: 10.1371/journal.pone.0101609
PMCID: PMC4103782

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Non-canonical roles for Yorkie and Drosophila Inhibitor of Apoptosis 1 in epithelial tube size control.PMID 25036253Read ↗

Elucidation of a universal size-control mechanism in Drosophila and mammals.Semantic proximity Read ↗

The Hippo Pathway Targets Rae1 to Regulate Mitosis and Organ Size and to Feed Back to Regulate Upstream Components Merlin, Hippo, and Warts.Semantic proximity Read ↗

The bantam microRNA is a target of the hippo tumor-suppressor pathway.Semantic proximity Read ↗

Ajuba LIM proteins are negative regulators of the Hippo signaling pathway.Semantic proximity Read ↗

Fat cadherin modulates organ size in Drosophila via the Salvador/Warts/Hippo signaling pathway.Semantic proximity Read ↗

Hippo signaling pathway and organ size control.Semantic proximity Read ↗

Dmp53 activates the Hippo pathway to promote cell death in response to DNA damage.Semantic proximity Read ↗

The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control.Semantic proximity Read ↗

Serrano (sano) functions with the planar cell polarity genes to control tracheal tube length.Semantic proximity Read ↗

Epithelial polarity proteins regulate Drosophila tracheal tube size in parallel to the luminal matrix pathway.Semantic proximity Read ↗

Hippo pathway perturbation disrupts cell fate control in the <i>Drosophila</i> eyeSemantic proximity Read ↗

Scaling the Drosophila Wing: TOR-Dependent Target Gene Access by the Hippo Pathway Transducer Yorkie.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.