Article
Epithelial polarity proteins regulate Drosophila tracheal tube size in parallel to the luminal matrix pathway.
Current biology : CB - 12 Jan 2010
Laprise Patrick, Paul Sarah M, Boulanger Jim, Robbins Renée M, Beitel Greg J, Tepass Ulrich
Abstract excerpt
Regulation of epithelial tube size is critical for organ function. However, the mechanisms of tube size control remain poorly understood. In the Drosophila trachea, tube dimensions are regulated by a luminal extracellular matrix (ECM). ECM organization requires apical (luminal) secretion of the p...
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