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Article

Hippo signaling pathway and organ size control.

Fly - 1 Jan 2000

Zhang Lei, Yue Tao, Jiang Jin

Abstract excerpt

Initially discovered in Drosophila, the Hippo (Hpo) pathway has been recognized as a conserved signaling pathway that controls organ size during development by restricting cell growth and proliferation and by promoting apoptosis. In addition, abnormal activities of several Hpo pathway components have been implicated in human cancer. Here, we review the current understanding of the molecular and cellular basis of...

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Identifiers

PMID: 19164949
DOI: 10.4161/fly.3.1.7788
PMCID: PMC6404755

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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