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Article

Association between gene polymorphisms of connective tissue growth factor and the progression of chronic liver disease associated with hepatitis C.

Internal medicine (Tokyo, Japan) - 1 Jan 2014

Miyoshi Kenichi, Ikebuchi Yuichiro, Ishida Chihiro, Okamoto Kinya, Murawaki Yoshikazu

Abstract excerpt

OBJECTIVE: Fibrogenic cytokines, such as transforming growth factor-beta 1 play a central role in the progression of liver fibrosis. Recently, functional gene polymorphisms in these cytokines have been identified, and some reports have validated the presence of associations between these polymorphisms and disease progression. Connective tissue growth factor (CTGF) is a stimulating factor for fibroblast...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25030555
DOI: 10.2169/internalmedicine.53.1864

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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