Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Increased fibrosis progression rates in hepatitis C patients carrying the prothrombin G20210A mutation.

World journal of gastroenterology - 7 Dec 2011

Maharshak Nitsan, Halfon Philippe, Deutsch Varda, Peretz Hava, Berliner Shlomo, Fishman Sigal, Zelber-Sagi Shira, Rozovski Uri, Leshno Moshe, Oren Ran

Abstract excerpt

AIM: To examine whether hepatitis C virus (HCV)-infected patients who carry hypercoagulable mutations suffer from increased rates of liver fibrosis. METHODS: We analyzed DNA samples of 168 HCV patients for three common hypercoagulable gene mutations: prothrombin 20210 (PT20210), factor V Leiden (FV Leiden) and methylene tetrahydrofolate reductase (MTHFR). The patients were consecutively recruited as part of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disease Progression
Share to Factor V

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Hepatitis C

Share to Liver Cirrhosis

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Prothrombin

Share to Thrombophilia

Source

Open in PubMed Open full text

Identifiers

PMID: 22174551
DOI: 10.3748/wjg.v17.i45.5007
PMCID: PMC3236579

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Increased fibrosis progression rates in hepatitis C patients carrying the prothrombin G20210A mutation.PMID 22174551Read ↗

Impact of prothrombin and factor V Leiden mutations on the progression of fibrosis in patients with chronic hepatitis C.Semantic proximity Read ↗

Factor V Leiden polymorphism and the rate of fibrosis development in chronic hepatitis C virus infection.Semantic proximity Read ↗

Association between gene polymorphisms of connective tissue growth factor and the progression of chronic liver disease associated with hepatitis C.Semantic proximity Read ↗

Impact of common risk factors of fibrosis progression in chronic hepatitis C.Semantic proximity Read ↗

Recognition of genetic factors influencing the progression of hepatitis C : potential for personalized therapy.Semantic proximity Read ↗

Association of thrombogenic genes polymorphisms with hepatocellular carcinoma in HCV Egyptian patients.Semantic proximity Read ↗

A combination of genetic polymorphisms increases the risk of progressive disease in chronic hepatitis CSemantic proximity Read ↗

Genotype 3 is associated with accelerated fibrosis progression in chronic hepatitis C.Semantic proximity Read ↗

Host genetic factors influence disease progression in chronic hepatitis CSemantic proximity Read ↗

Association of polymorphisms of the transforming growth factor-beta1 gene with the rate of progression of HCV-induced liver fibrosis.Semantic proximity Read ↗

Prothrombotic genetic risk factors are associated with an increased risk of liver fibrosis in the general population: The Rotterdam Study.Semantic proximity Read ↗

The impact of inherited prothrombotic risk factors on individuals chronically infected with hepatitis C virus from a single source.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.