Article
Transforming growth factor-beta1 gene polymorphisms are associated with progression of liver fibrosis in Caucasians with chronic hepatitis C infection.
World journal of gastroenterology - 7 Apr 2005
Wang Hao, Mengsteab Senait, Tag Carmen-G, Gao Chun-Fang, Hellerbrand Claus, Lammert Frank, Gressner Axel-M, Weiskirchen Ralf
Abstract excerpt
AIM: Considerable attention is focused on polymorphisms in the gene encoding transforming growth factor-beta1 (TGF-beta1), a multifunctional cytokine that is in turn a potent growth inhibitor involved in wound healing and differentiation. In humans, it promotes the pathogenesis of organ fibrosis, atherosclerosis, cancer, autoimmune and inflammatory diseases, keloid disease, and hypertrophic scarring. For this...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
