Polymorphisms of interferon gamma gene and risk of hepatocellular carcinoma in Korean patients with chronic hepatitis B viral infection.

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Polymorphisms of interferon gamma gene and risk of hepatocellular carcinoma in Korean patients with chronic hepatitis B viral infection.

Hepato-gastroenterology - 1 Jan 2000

Kim Hak-Jae, Chung Joo-Ho, Shin Hyun Phil, Jeon Jung Won, Park Jae Jun, Cha Jae Myung, Joo Kwang Ro, Lee Joung Il

Abstract excerpt

BACKGROUNDS/AIMS: Increasing evidence supports the contribution of the pro-/anti-inflammatory cytokine balance and genetic factors to hepatocellular carcinoma (HCC). Here, we investigated whether genetic interferon gamma polymorphisms were associated with HCC in Korean patients with chronic hepatitis B. METHODOLOGY: We genotyped a single nucleotide polymorphism (SNP, rs2430561, +874A/T) and a microsatellite...

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PMID: 24719951

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