Impact of TGF-β1 Gene Polymorphism (rs1800469) on Treatment Response to Pegylated Interferon/Ribavirin in Iranian Patients with Hepatitis C.

doi:10.7754/clin.lab.2015.150807

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Impact of TGF-β1 Gene Polymorphism (rs1800469) on Treatment Response to Pegylated Interferon/Ribavirin in Iranian Patients with Hepatitis C.

Clinical laboratory - 1 Jan 2016

Larijani Mona Sadat, Rad Leila Naghizadeh, Nikbin Mehri, Bahiraei Narges, Javadi Foozieh, Daneshvar Mahtab, Aghasadeghi Mohammad Reza, Rahimi Pooneh, Siadat Seyed Davar, Zabihollahi Rezvan, Sadat Seyed Mehdi

Abstract excerpt

BACKGROUND: Hepatitis C virus as a major cause of chronic liver disease affects more than 170 million people worldwide. Recent studies have claimed that single nucleotide polymorphisms (SNPs) for the transforming growth factor-β1 (TGF-β1) gene were strongly associated with the antiviral treatment response. Thus, the present study aimed at the determination of distribution of the rs1800469 (C/T) polymorphism among...

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PMID: 27215079
DOI: 10.7754/clin.lab.2015.150807

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