Article
Functional gene polymorphisms of interleukin-10 are associated with liver disease progression in Japanese patients with hepatitis C virus infection.
Internal medicine (Tokyo, Japan) - 1 Jan 2011
Ishida Chihiro, Ikebuchi Yuichiro, Okamoto Kinya, Murawaki Yoshikazu
Abstract excerpt
OBJECTIVE: The inter-individual difference in response to liver injury appears to be important in the progression of liver fibrosis. Interleukin 10 (IL-10) is an anti-inflammatory cytokine, and several functional gene polymorphisms have been found. The aim of this study was to examine the possible association of IL-10 polymorphisms with the progression of liver fibrosis in hepatitis C virus (HCV)-related chronic...
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