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Article

A potentially functional variant in the serotonin transporter gene is associated with premenopausal and perimenopausal hot flashes.

Menopause (New York, N.Y.) - 1 Jan 2015

Montasser May E, Ziv-Gal Ayelet, Brown Jessica P, Flaws Jodi A, Merchenthaler Istvan

Abstract excerpt

OBJECTIVE: An increase in the use of selective serotonin reuptake inhibitors (SSRIs) and/or serotonin-norepinephrine reuptake inhibitors (SNRIs) to relieve menopausal hot flashes (HFs) has been observed recently. However, response to them has been heterogeneous. We hypothesized that this heterogeneity might be partially attributed to genetic variations in genes encoding the serotonin and/or norepinephrine...

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Identifiers

PMID: 25026114
DOI: 10.1097/GME.0000000000000291
PMCID: PMC4270913

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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