Article
Sequence analysis of the serotonin transporter and associations with antidepressant response.
Biological psychiatry - 1 Sept 2005
Kraft Jeffrey B, Slager Susan L, McGrath Patrick J, Hamilton Steven P
Abstract excerpt
BACKGROUND: The serotonin transporter is the molecular target of many antidepressants, and the gene (SLC6A4) encoding this protein has been associated with response to selective serotonin reuptake inhibitors (SSRIs). We sought to test further the hypothesis that SLC6A4 is associated with SSRI response by resequencing this gene in subjects with major depression. METHODS: The sequence of all exons, parts of all...
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