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Article

Joint effects of smoking and gene variants involved in sex steroid metabolism on hot flashes in late reproductive-age women.

The Journal of clinical endocrinology and metabolism - 1 Jun 2012

Butts Samantha F, Freeman Ellen W, Sammel Mary D, Queen Kaila, Lin Hui, Rebbeck Timothy R

Abstract excerpt

BACKGROUND: Although smoking has a known association with hot flashes, the factors distinguishing smokers at greatest risk for menopausal symptoms have not been well delineated. Recent evidence supports a relationship between menopausal symptoms and variants in several genes encoding enzymes that metabolize substrates such as sex steriods, xenobiotics, and catechols. It is currently not known whether the impact...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22466345
DOI: 10.1210/jc.2011-2216
PMCID: PMC3387409

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Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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