Article
Contribution of adenosine related genes to the risk of depression with disturbed sleep.
Journal of affective disorders - 1 Oct 2010
Gass Natalia, Ollila Hanna M, Utge Siddheshwar, Partonen Timo, Kronholm Erkki, Pirkola Sami, Suhonen Johanna, Silander Kaisa, Porkka-Heiskanen Tarja, Paunio Tiina
Abstract excerpt
BACKGROUND: Most patients with major depression report problems in their sleep: insomnia, early morning awakenings and fatigue correlating with poor sleep quality. One of the key substances regulating sleep is adenosine. We hypothesized that variations in polymorphic sites of adenosine related genes may predispose to depression with sleep disturbances. METHODS: We selected 117 single nucleotide polymorphisms from...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
