Article
5-HTR1A, 5-HTR2A, 5-HTR6, TPH1 and TPH2 polymorphisms and major depression.
Neuroreport - 5 Aug 2009
Illi Ari, Setälä-Soikkeli Eija, Viikki Merja, Poutanen Outi, Huhtala Heini, Mononen Nina, Lehtimäki Terho, Leinonen Esa, Kampman Olli
Abstract excerpt
Genes that regulate the serotonin signalling system are potential targets for research in the aetiology of mood disorders and also in the treatment response of serotonin reuptake inhibitors. In this study, we evaluated the association of seven serotonin signal transduction-linked single nucleotide polymorphisms [HTR1A (rs6295), HTR2A (rs6313, rs6311 and rs7997012), HTR6 (rs1805054), TPH1 () and TPH2...