Article
Deregulation of purine pathway in Bacillus subtilis and its use in riboflavin biosynthesis.
Microbial cell factories - 15 Jul 2014
Shi Ting, Wang Yongcheng, Wang Zhiwen, Wang Guanglu, Liu Dingyu, Fu Jing, Chen Tao, Zhao Xueming
Abstract excerpt
BACKGROUND: Purine nucleotides are essential metabolites for living organisms because they are involved in many important processes, such as nucleic acid synthesis, energy supply, and biosynthesis of several amino acids and riboflavin. Owing to the pivotal roles of purines in cell physiology, the pool of intracellular purine nucleotides must be maintained under strict control, and hence the de novo purine...
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