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Article

Riboswitches control fundamental biochemical pathways in Bacillus subtilis and other bacteria.

Cell - 30 May 2003

Mandal Maumita, Boese Benjamin, Barrick Jeffrey E, Winkler Wade C, Breaker Ronald R

Abstract excerpt

Riboswitches are metabolite binding domains within certain messenger RNAs that serve as precision sensors for their corresponding targets. Allosteric rearrangement of mRNA structure is mediated by ligand binding, and this results in modulation of gene expression. We have identified a class of riboswitches that selectively recognizes guanine and becomes saturated at concentrations as low as 5 nM. In Bacillus...

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Share to Gene Expression Regulation, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12787499
DOI: 10.1016/s0092-8674(03)00391-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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