Article
E(y)1/TAF9 mediates the transcriptional output of Notch signaling in Drosophila.
Journal of cell science - 1 Sept 2014
Xie Gengqiang, Yu Zhongsheng, Jia Dongyu, Jiao Renjie, Deng Wu-Min
Abstract excerpt
Transcriptional activation of Notch signaling targets requires the formation of a ternary complex that involves the intracellular domain of the Notch receptor (NICD), DNA-binding protein Suppressor of Hairless [Su(H), RPBJ in mammals] and coactivator Mastermind (Mam). Here, we report that E(y)1/TAF9, a component of the transcription factor TFIID complex, interacts specifically with the NICD-Su(H)-Mam complex to...
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