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Article

Investigating the genetic circuitry of mastermind in Drosophila, a notch signal effector.

Genetics - 1 Dec 2007

Kankel Mark W, Hurlbut Gregory D, Upadhyay Geeta, Yajnik Vijay, Yedvobnick Barry, Artavanis-Tsakonas Spyros

Abstract excerpt

Notch signaling regulates multiple developmental processes and is implicated in various human diseases. Through use of the Notch transcriptional co-activator mastermind, we conducted a screen for Notch signal modifiers using the Exelixis collection of insertional mutations, which affects approximately 50% of the Drosophila genome, recovering 160 genes never before associated with Notch, extending the previous...

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Identifiers

PMID: 18073442
DOI: 10.1534/genetics.107.080994
PMCID: PMC2219471

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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