Article
A Network of Chromatin Factors Is Regulating the Transition to Postembryonic Development in Caenorhabditis elegans.
G3 (Bethesda, Md.) - 9 Feb 2017
Erdelyi Peter, Wang Xing, Suleski Marina, Wicky Chantal
Abstract excerpt
Mi2 proteins are evolutionarily conserved, ATP-dependent chromatin remodelers of the CHD family that play key roles in stem cell differentiation and reprogramming. In Caenorhabditis elegans, the let-418 gene encodes one of the two Mi2 homologs, which is part of at least two chromatin complexes, namely the Nucleosome Remodeling and histone Deacetylase (NuRD) complex and the MEC complex, and functions in larval...
Topics
- Animals
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Chromatin
- Chromatin Assembly and Disassembly
- DNA-Binding Proteins
- Embryonic Development
- Genome
- Larva
- Mi-2 Nucleosome Remodeling and Deacetylase Complex
