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Article

Drosophila myt1 is the major cdk1 inhibitory kinase for wing imaginal disc development.

Genetics - 1 Dec 2008

Jin Zhigang, Homola Ellen, Tiong Stanley, Campbell Shelagh D

Abstract excerpt

Mitosis is triggered by activation of Cdk1, a cyclin-dependent kinase. Conserved checkpoint mechanisms normally inhibit Cdk1 by inhibitory phosphorylation during interphase, ensuring that DNA replication and repair is completed before cells begin mitosis. In metazoans, this regulatory mechanism is also used to coordinate cell division with critical developmental processes, such as cell invagination. Two types of...

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Identifiers

PMID: 18940789
DOI: 10.1534/genetics.108.093195
PMCID: PMC2600946

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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