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Article

Hedgehog-stimulated stem cells depend on non-canonical activity of the Notch co-activator Mastermind.

Development (Cambridge, England) - 1 Jul 2009

Vied Cynthia, Kalderon Daniel

Abstract excerpt

Normal self-renewal of follicle stem cells (FSCs) in the Drosophila ovary requires Hedgehog (Hh) signaling. Excess Hh signaling, induced by loss of patched (ptc), causes cell-autonomous duplication of FSCs. We have used a genetic screen to identify Mastermind (Mam), the Notch pathway transcriptio...

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Identifiers

PMID: 19474148
DOI: 10.1242/dev.035329
PMCID: PMC2729338

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19474148-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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