Article
Endothelial paxillin and focal adhesion kinase (FAK) play a critical role in neutrophil transmigration.
European journal of immunology - 1 Feb 2012
Parsons Sean A, Sharma Ritu, Roccamatisi Dawn L, Zhang Hong, Petri Björn, Kubes Paul, Colarusso Pina, Patel Kamala D
Abstract excerpt
During an inflammatory response, endothelial cells undergo morphological changes to allow for the passage of neutrophils from the blood vessel to the site of injury or infection. Although endothelial cell junctions and the cytoskeleton undergo reorganization during inflammation, little is known about another class of cellular structures, the focal adhesions. In this study, we examined several focal adhesion...
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