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Article

Copy number polymorphisms near SLC2A9 are associated with serum uric acid concentrations.

BMC genetics - 9 Jul 2014

Scharpf Robert B, Mireles Lynn, Yang Qiong, Köttgen Anna, Ruczinski Ingo, Susztak Katalin, Halper-Stromberg Eitan, Tin Adrienne, Cristiano Stephen, Chakravarti Aravinda, Boerwinkle Eric, Fox Caroline S, Coresh Josef, Linda Kao Wen Hong

Abstract excerpt

BACKGROUND: Hyperuricemia is associated with multiple diseases, including gout, cardiovascular disease, and renal disease. Serum urate is highly heritable, yet association studies of single nucleotide polymorphisms (SNPs) and serum uric acid explain a small fraction of the heritability. Whether copy number polymorphisms (CNPs) contribute to uric acid levels is unknown. RESULTS: We assessed copy number on a...

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Share to DNA Copy Number Variations
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glucose Transport Proteins, Facilitative

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Identifiers

PMID: 25007794
DOI: 10.1186/1471-2156-15-81
PMCID: PMC4118309

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CNP

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