Article
A genome-wide association study identifies common variants influencing serum uric acid concentrations in a Chinese population.
BMC medical genomics - 11 Feb 2014
Yang Binyao, Mo Zengnan, Wu Chen, Yang Handong, Yang Xiaobo, He Yunfeng, Gui Lixuan, Zhou Li, Guo Huan, Zhang Xiaomin, Yuan Jing, Dai Xiayun, Li Jun, Qiu Gaokun, Huang Suli, Deng Qifei, Feng Yingying, Guan Lei, Hu Die, Zhang Xiao, Wang Tian, Zhu Jiang, Min Xinwen, Lang Mingjian, Li Dongfeng, Hu Frank B, Lin Dongxin, Wu Tangchun, He Meian
Abstract excerpt
BACKGROUND: Uric acid (UA) is a complex phenotype influenced by both genetic and environmental factors as well as their interactions. Current genome-wide association studies (GWASs) have identified a variety of genetic determinants of UA in Europeans; however, such studies in Asians, especially in Chinese populations remain limited. METHODS: A two-stage GWAS was performed to identify single nucleotide...
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