Article
Association between SLC2A9 transporter gene variants and uric acid phenotypes in African American and white families.
Rheumatology (Oxford, England) - 1 May 2011
Rule Andrew D, de Andrade Mariza, Matsumoto Martha, Mosley Tom H, Kardia Sharon, Turner Stephen T
Abstract excerpt
OBJECTIVES: SLC2A9 gene variants associate with serum uric acid in white populations, but little is known about African American populations. Since SLC2A9 is a transporter, gene variants may be expected to associate more closely with the fractional excretion of urate, a measure of renal tubular transport, than with serum uric acid, which is influenced by production and extrarenal clearance. METHODS: Genotypes of...
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