Article
Abundant local interactions in the 4p16.1 region suggest functional mechanisms underlying SLC2A9 associations with human serum uric acid.
Human molecular genetics - 1 Oct 2014
Wei Wen-Hua, Guo Yunfei, Kindt Alida S D, Merriman Tony R, Semple Colin A, Wang Kai, Haley Chris S
Abstract excerpt
Human serum uric acid concentration (SUA) is a complex trait. A recent meta-analysis of multiple genome-wide association studies (GWAS) identified 28 loci associated with SUA jointly explaining only 7.7% of the SUA variance, with 3.4% explained by two major loci (SLC2A9 and ABCG2). Here we examin...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
