Article
A genome-wide association study of serum uric acid in African Americans.
BMC medical genomics - 4 Feb 2011
Charles Bashira A, Shriner Daniel, Doumatey Ayo, Chen Guanjie, Zhou Jie, Huang Hanxia, Herbert Alan, Gerry Norman P, Christman Michael F, Adeyemo Adebowale, Rotimi Charles N
Abstract excerpt
BACKGROUND: Uric acid is the primary byproduct of purine metabolism. Hyperuricemia is associated with body mass index (BMI), sex, and multiple complex diseases including gout, hypertension (HTN), renal disease, and type 2 diabetes (T2D). Multiple genome-wide association studies (GWAS) in individuals of European ancestry (EA) have reported associations between serum uric acid levels (SUAL) and specific genomic...
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