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Article

Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study.

Lancet (London, England) - 6 Dec 2008

Dehghan Abbas, Köttgen Anna, Yang Qiong, Hwang Shih-Jen, Kao Wh Linda, Rivadeneira Fernando, Boerwinkle Eric, Levy Daniel, Hofman Albert, Astor Brad C, Benjamin Emelia J, van Duijn Cornelia M, Witteman Jacqueline C, Coresh Josef, Fox Caroline S

Abstract excerpt

BACKGROUND: Hyperuricaemia, a highly heritable trait, is a key risk factor for gout. We aimed to identify novel genes associated with serum uric acid concentration and gout. METHODS: Genome-wide association studies were done for serum uric acid in 7699 participants in the Framingham cohort and in 4148 participants in the Rotterdam cohort. Genome-wide significant single nucleotide polymorphisms (SNPs) were...

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Identifiers

PMID: 18834626
DOI: 10.1016/S0140-6736(08)61343-4
PMCID: PMC2803340

Genes

ABCG2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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