Article
A 'complexity' of urate transporters.
Kidney international - 1 Sept 2010
Wright Alan F, Rudan Igor, Hastie Nicholas D, Campbell Harry
Abstract excerpt
Genetic variation in the SLC2A9 gene is a new genetic risk factor for low fractional excretion of uric acid, hyperuricemia, and gout. Its gene product, GLUT9, was previously known as a type II glucose/fructose transporter but is now known to function as a high-capacity uric acid transporter that is expressed in kidney, liver, and several other tissues. Follow-up meta-analyses, including one with data from 28,141...
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