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Article

A population-specific low-frequency variant of SLC22A12 (p.W258*) explains nearby genome-wide association signals for serum uric acid concentrations among Koreans.

PloS one - 1 Jan 2020

Im Sun-Wha, Chae Jeesoo, Son Ho-Young, Cho Belong, Kim Jong-Il, Park Jin-Ho

Abstract excerpt

Prolonged hyperuricemia is a cause of gout and an independent risk factor for chronic health conditions including diabetes and chronic kidney diseases. Genome-wide association studies (GWASs) for serum uric acid (SUA) concentrations have repeatedly confirmed genetic loci including those encoding uric acid transporters such as ABCG2 and SLC9A2. However, many single nucleotide polymorphisms (SNPs) found in GWASs...

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Identifiers

PMID: 32271837
DOI: 10.1371/journal.pone.0231336
PMCID: PMC7145145

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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