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Article

Replication of the effect of SLC2A9 genetic variation on serum uric acid levels in American Indians.

European journal of human genetics : EJHG - 1 Jul 2014

Voruganti V Saroja, Franceschini Nora, Haack Karin, Laston Sandra, MacCluer Jean W, Umans Jason G, Comuzzie Anthony G, North Kari E, Cole Shelley A

Abstract excerpt

Increased serum uric acid (SUA) or hyperuricemia, a risk factor for gout, renal and cardiovascular diseases, is caused by either increased production or decreased excretion of uric acid or a mix of both. The solute carrier protein 2 family, member 9 (SLC2A9) gene encodes a transporter that mediates urate flux across the renal proximal tubule. Genome-wide association studies have consistently shown the association...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glomerular Filtration Rate

Share to Glucose Transport Proteins, Facilitative

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Share to Polymorphism, Genetic

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Source

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Identifiers

PMID: 24301058
DOI: 10.1038/ejhg.2013.264
PMCID: PMC4060115

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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