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Article

IL-12-secreting CD19-targeted cord blood-derived T cells for the immunotherapy of B-cell acute lymphoblastic leukemia.

Leukemia - 1 Feb 2015

Pegram H J, Purdon T J, van Leeuwen D G, Curran K J, Giralt S A, Barker J N, Brentjens R J

Abstract excerpt

Disease relapse or progression is a major cause of death following umbilical cord blood (UCB) transplantation (UCBT) in patients with high-risk, relapsed or refractory acute lymphoblastic leukemia (ALL). Adoptive transfer of donor-derived T cells modified to express a tumor-targeted chimeric anti...

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Source

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Identifiers

PMID: 25005243
DOI: 10.1038/leu.2014.215
PMCID: PMC5189717

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25005243-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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