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Article

A novel method using blinatumomab for efficient, clinical-grade expansion of polyclonal T cells for adoptive immunotherapy.

Journal of immunology (Baltimore, Md. : 1950) - 1 Nov 2014

Golay Josée, D'Amico Anna, Borleri Gianmaria, Bonzi Michela, Valgardsdottir Rut, Alzani Rachele, Cribioli Sabrina, Albanese Clara, Pesenti Enrico, Finazzi Maria Chiara, Quaresmini Giulia, Nagorsen Dirk, Introna Martino, Rambaldi Alessandro

Abstract excerpt

Current treatment of chronic lymphocytic leukemia (CLL) patients often results in life-threatening immunosuppression. Furthermore, CLL is still an incurable disease due to the persistence of residual leukemic cells. These patients may therefore benefit from immunotherapy approaches aimed at immunoreconstitution and/or the elimination of residual disease following chemotherapy. For these purposes, we designed a...

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Share to Antibodies, Bispecific
Share to Antigens, Surface

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytotoxicity, Immunologic

Share to Immunotherapy, Adoptive

Share to Interleukin-2

Share to Leukemia, Lymphocytic, Chronic, B-Cell

Share to Programmed Cell Death 1 Receptor

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Source

Identifiers

PMID: 25267972
DOI: 10.4049/jimmunol.1401550

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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