Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High-throughput single nucleotide variant discovery in E14 mouse embryonic stem cells provides a new reference genome assembly.

Genomics - 1 Aug 2014

Incarnato Danny, Krepelova Anna, Neri Francesco

Abstract excerpt

Mouse E14 embryonic stem cells (ESCs) are a well-characterized and widespread used ESC line, often employed for genome-wide studies involving next generation sequencing analysis. More than 2×10(9) sequences made on Illumina platform derived from the genome of E14 ESCs were used to build a database of about 2.7×10(6) single nucleotide variants (SNVs). The identified variants are enriched in intergenic regions, but...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Databases, Factual
Share to DNA, Intergenic
Share to Embryonic Stem Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome

Share to Genomics

Share to High-Throughput Nucleotide Sequencing

Share to Regulatory Sequences, Nucleic Acid

Share to Reproducibility of Results

Source

Identifiers

PMID: 25004115
DOI: 10.1016/j.ygeno.2014.06.007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High-throughput single nucleotide variant discovery in E14 mouse embryonic stem cells provides a new reference genome assembly.PMID 25004115Read ↗

High Coverage Highly Accurate Long-Read Sequencing of a Mouse Neuronal Cell Line Using the PacBio Revio SequencerSemantic proximity Read ↗

Resolution of structural variation in diverse mouse genomes reveals chromatin remodeling due to transposable elementsSemantic proximity Read ↗

The fine-scale architecture of structural variants in 17 mouse genomes.Semantic proximity Read ↗

Massively parallel sequencing of the mouse exome to accurately identify rare, induced mutations: an immediate source for thousands of new mouse models.Semantic proximity Read ↗

Molecular and genetic heterogeneity in iPSCs derived from an outbred laboratory mouse populationSemantic proximity Read ↗

Retrotransposon instability dominates the acquired mutation landscape of mouse induced pluripotent stem cellsSemantic proximity Read ↗

Whole Genome Sequence of Two Wild-Derived Mus musculus domesticus Inbred Strains, LEWES/EiJ and ZALENDE/EiJ, with Different Diploid Numbers.Semantic proximity Read ↗

CGDSNPdb: a database resource for error-checked and imputed mouse SNPs.Semantic proximity Read ↗

A customized and versatile high-density genotyping array for the mouse.Semantic proximity Read ↗

Retrotransposon instability dominates the acquired mutation landscape of mouse induced pluripotent stem cells.Semantic proximity Read ↗

A revamped rat reference genome improves the discovery of genetic diversity in laboratory rats.Semantic proximity Read ↗

Stem cell transcriptome profiling via massive-scale mRNA sequencing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.