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The evolution of enzyme function in the isomerases

1 Jun 2014

Abstract excerpt

The advent of computational approaches to measure functional similarity between enzymes adds a new dimension to existing evolutionary studies based on sequence and structure. This paper reviews research efforts aiming to understand the evolution of enzyme function in superfamilies, presenting a novel strategy to provide an overview of the evolution of enzymes belonging to an individual EC class, using the...

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Identifiers

PMID: 25000289
DOI: 10.1016/j.sbi.2014.06.002

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