Article
CorNet: Assigning function to networks of co-evolving residues by automated literature mining.
PloS one - 1 Jan 2017
van den Bergh Tom, Tamo Giorgio, Nobili Alberto, Tao Yifeng, Tan Tianwei, Bornscheuer Uwe T, Kuipers Remko K P, Vroling Bas, de Jong René M, Subramanian Kalyanasundaram, Schaap Peter J, Desmet Tom, Nidetzky Bernd, Vriend Gert, Joosten Henk-Jan
Abstract excerpt
CorNet is a web-based tool for the analysis of co-evolving residue positions in protein super-family sequence alignments. CorNet projects external information such as mutation data extracted from literature on interactively displayed groups of co-evolving residue positions to shed light on the functions associated with these groups and the residues in them. We used CorNet to analyse six enzyme super-families and...
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