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Article

The stem cell factor/Kit signalling pathway regulates mitochondrial function and energy expenditure.

Nature communications - 7 Jul 2014

Huang Zan, Ruan Hai-Bin, Xian Li, Chen Weiqian, Jiang Shujun, Song Anying, Wang Qinghua, Shi Peiliang, Gu Xingxing, Gao Xiang

Abstract excerpt

Cell growth is tightly coupled with mitochondrial biogenesis in order to maintain energy and organelle homeostasis. Receptor tyrosine kinase Kit and its ligand, stem cell factor (SCF), play a critical role in the growth and survival of multiple cell lineages. Here we report that the expression of...

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Source

Identifiers

PMID: 24999927
DOI: 10.1038/ncomms5282

Genes

PGC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24999927-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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