Article
MitoNEET-mediated effects on browning of white adipose tissue.
Nature communications - 28 May 2014
Kusminski Christine M, Park Jiyoung, Scherer Philipp E
Abstract excerpt
MitoNEET is an outer mitochondrial membrane protein that, upon overexpression in white adipose tissue (WAT), exerts a positive impact on tissue expansion and whole-body lipid and carbohydrate homeostasis by altering mitochondrial matrix iron metabolism. Here we determine the key transcriptional events in subcutaneous WAT of mice in response to mitoNEET overexpression and a high-fat diet (HFD). Microarray analyses...
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