Article
Defective mitochondrial morphology and bioenergetic function in mice lacking the transcription factor Yin Yang 1 in skeletal muscle.
Molecular and cellular biology - 1 Aug 2012
Blättler Sharon M, Verdeguer Francisco, Liesa Marc, Cunningham John T, Vogel Rutger O, Chim Helen, Liu Huifei, Romanino Klaas, Shirihai Orian S, Vazquez Francisca, Rüegg Markus A, Shi Yang, Puigserver Pere
Abstract excerpt
The formation, distribution, and maintenance of functional mitochondria are achieved through dynamic processes that depend strictly on the transcription of nuclear genes encoding mitochondrial proteins. A large number of these mitochondrial genes contain binding sites for the transcription factor...
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