Article
Bacterial lantibiotics: strategies to improve therapeutic potential.
Current protein & peptide science - 1 Feb 2005
Cotter Paul D, Hill Colin, Ross R Paul
Abstract excerpt
Lantibiotics are ribosomally-synthesised antimicrobial peptides produced by Gram-positive bacteria that are characterised by the presence of lanthionine and/or methyllanthionine residues. Other unusual post-translationally modified amino acids, most frequently dehydroalanine and dehydrobutyrine, can also be present. While it has been frequently suggested that these peptides have the potential to be utilised in a...
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