Article
Bacterial lantibiotics: strategies to improve therapeutic potential.
Current protein & peptide science - 1 Feb 2005
Cotter Paul D, Hill Colin, Ross R Paul
Abstract excerpt
Lantibiotics are ribosomally-synthesised antimicrobial peptides produced by Gram-positive bacteria that are characterised by the presence of lanthionine and/or methyllanthionine residues. Other unusual post-translationally modified amino acids, most frequently dehydroalanine and dehydrobutyrine, can also be present. While it has been frequently suggested that these peptides have the potential to be utilised in a...
Topics
- Alanine
- Amino Acid Sequence
- Amino Acids
- Anti-Bacterial Agents
- Bacteria
- Molecular Conformation
- Molecular Sequence Data
- Mutation
- Peptides
- Sequence Homology, Amino Acid
- Sulfhydryl Compounds