Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

One-pot synthesis of class II lanthipeptide bovicin HJ50 via an engineered lanthipeptide synthetase.

Scientific reports - 7 Dec 2016

Wang Jian, Ge Xiaoxuan, Zhang Li, Teng Kunling, Zhong Jin

Abstract excerpt

Lanthipeptides are a large class of bacteria-produced, ribosomally-synthesized and post-translationally modified peptides. They are recognized as peptide antibiotics because most of them exhibit potent antimicrobial activities against Gram-positive bacteria especially those that are phylogenetically related to producers. Maturation of class II lanthipeptide like bovicin HJ50 undergoes precursor modification by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Bacteriocins
Share to Catalysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to Enzyme Activation

Share to Models, Molecular

Share to Peptide Synthases

Share to Protein Conformation

Source

Open in PubMed Open full text

Identifiers

PMID: 27924934
DOI: 10.1038/srep38630
PMCID: PMC5141572

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

One-pot synthesis of class II lanthipeptide bovicin HJ50 via an engineered lanthipeptide synthetase.PMID 27924934Read ↗

Dissecting the catalytic and substrate binding activity of a class II lanthipeptide synthetase BovM.Semantic proximity Read ↗

Multipronged approach for engineering novel peptide analogues of existing lantibioticsSemantic proximity Read ↗

Engineering dehydro amino acids and thioethers into peptides using lacticin 481 synthetase.Semantic proximity Read ↗

Identification of ligand specificity determinants in lantibiotic bovicin HJ50 and the receptor BovK, a multitransmembrane histidine kinase.Semantic proximity Read ↗

Investigation of the Biosynthesis of the Lasso Peptide Chaxapeptin Using an E. coli-Based Production System.Semantic proximity Read ↗

From discovery to potential application: engineering a novel M23 peptidase to combat Listeria monocytogenesSemantic proximity Read ↗

Lacticin 481: in vitro reconstitution of lantibiotic synthetase activity.Semantic proximity Read ↗

Maturation by LctT is required for biosynthesis of full-length lantibiotic lacticin 481.Semantic proximity Read ↗

Evolutionary and functional analysis of an NRPS condensation domain integrates β-lactam, ᴅ-amino acid, and dehydroamino acid synthesisSemantic proximity Read ↗

Targeted Modification of the Antimicrobial Peptide DGL13K Reveals a Naturally Optimized Sequence for Topical ApplicationsSemantic proximity Read ↗

Bacterial lantibiotics: strategies to improve therapeutic potential.Semantic proximity Read ↗

Evolution Inspired Engineering of MegasynthetasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.