Article

Structure-Activity Relationship Studies of Novel Gut-derived Lantibiotics Against Human Gut Commensals

2023-09-17

Abstract excerpt

Recent advances in sequencing techniques unveiled the vast potential of ribosomally synthesized and post-translationally modified peptides (RiPPs) encoded in microbiomes. Class I lantibiotics such as nisin A, widely used as a food preservative, have been investigated for their efficacy in killing pathogens. However, the impact of nisin and nisin-like class I lantibiotics on commensal bacteria residing in the human...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a1aaabc7-4d0e-5920-a512-7da84ef83c05
DOI: 10.1101/2023.09.15.557961

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Structure-Activity Relationship Studies of Novel Gut-derived Lantibiotics Against Human Gut CommensalsDOI 10.1101/2023.09.15.557961Read

First evidence of production of the lantibiotic nisin PSemantic proximity Read

Exposure and resistance to lantibiotics impact microbiota composition and functionSemantic proximity Read

Bacterial lantibiotics: strategies to improve therapeutic potential.Semantic proximity Read

Lantibiotics produced by Actinobacteria and their potential applications (a review)Semantic proximity Read

Increasing the Antimicrobial Activity of Nisin-Based Lantibiotics against Gram-Negative Pathogens.Semantic proximity Read

Nisin G is a novel nisin variant produced by a gut-derived <i>Streptococcus salivarius</i>Semantic proximity Read

Lantibiotics: an antimicrobial asset in combating aquaculture diseasesSemantic proximity Read

Multipronged approach for engineering novel peptide analogues of existing lantibioticsSemantic proximity Read

Health-associated gut bacteriocins target TLR4 to suppress intestinal inflammationSemantic proximity Read

In silico analysis highlights the frequency and diversity of type 1 lantibiotic gene clusters in genome sequenced bacteria.Semantic proximity Read

Lantibiotic-producing bacteria impact microbiome resilience and colonization resistanceSemantic proximity Read

Systematically investigating and identifying bacteriocins in the human gut microbiomeSemantic proximity Read