Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of ligand specificity determinants in lantibiotic bovicin HJ50 and the receptor BovK, a multitransmembrane histidine kinase.

The Journal of biological chemistry - 4 Apr 2014

Teng Kunling, Zhang Jie, Zhang Xue, Ge Xiaoxuan, Gao Yong, Wang Jian, Lin Yuheng, Zhong Jin

Abstract excerpt

Lantibiotic bovicin HJ50 is produced by Streptococcus bovis HJ50 and acts as the extracellular signal to autoregulate its own biosynthesis through BovK/R two-component system. Bovicin HJ50 shows a linear N-terminal and glubolar C-terminal structure, and the sensor histidine kinase BovK contains eight transmembrane segments lacking any extensive surface-exposed sensory domain. The signal recognition mechanism...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to Bacteriocins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histidine Kinase

Share to Mutation

Share to Protein Kinases

Share to Protein Structure, Tertiary

Share to Signal Transduction

Source

Open in PubMed Open full text

Identifiers

PMID: 24526683
DOI: 10.1074/jbc.M113.513150
PMCID: PMC3975027

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Identification of ligand specificity determinants in lantibiotic bovicin HJ50 and the receptor BovK, a multitransmembrane histidine kinase.PMID 24526683Read ↗

Dissecting the catalytic and substrate binding activity of a class II lanthipeptide synthetase BovM.Semantic proximity Read ↗

One-pot synthesis of class II lanthipeptide bovicin HJ50 via an engineered lanthipeptide synthetase.Semantic proximity Read ↗

Structural basis of the interaction of MbtH-like proteins, putative regulators of nonribosomal peptide biosynthesis, with adenylating enzymes.Semantic proximity Read ↗

Isolation of constitutive variants of a subfamily 10 histidine protein kinase (SppK) from Lactobacillus using random mutagenesis.Semantic proximity Read ↗

Heterologous Expression, Biosynthesis, and Mutagenesis of Type II Lantibiotics from Bacillus licheniformis in Escherichia coliSemantic proximity Read ↗

Identification of preferred substrate sequences of microbial transglutaminase from Streptomyces mobaraensis using a phage-displayed peptide librarySemantic proximity Read ↗

Identification of a region involved in the pheromone receptor function of the histidine kinase PlnB.Semantic proximity Read ↗

Obtaining an Ent35-MccV derivative with mutated hinge region that exhibits increased activity against Listeria monocytogenes and Escherichia coli.Semantic proximity Read ↗

Relatedness between the two-component lantibiotics lacticin 3147 and staphylococcin C55 based on structure, genetics and biological activity.Semantic proximity Read ↗

Structure of porphobilinogen synthase from Pseudomonas aeruginosa in complex with 5-fluorolevulinic acid suggests a double Schiff base mechanism.Semantic proximity Read ↗

Histidine-94 is the only important histidine residue in the melibiose permease of Escherichia coli.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.