Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MicroRNA-binding site SNPs in deregulated genes are associated with clinical outcome of non-small cell lung cancer.

Lung cancer (Amsterdam, Netherlands) - 1 Sept 2014

Xu Jiali, Tian Shengwang, Yin Zhiqiang, Wu Shuangshuang, Liu Lingxiang, Qian Yingying, Pei Dong, Gao Wen, Xu Jing, Yin Yongmei, Liu Ping, Shu Yongqian

Abstract excerpt

BACKGROUND: Single-nucleotide polymorphisms (SNPs) in 3'-untranslated regions of cancer-related genes might affect regulation by microRNAs and contribute to cancer patients' outcome. METHODS: We used public databases to identify SNPs within miRNA-binding sites in deregulated genes in non-small cell lung cancer (NSCLC). A total of 13 SNPs in 10 genes were included and genotyped by SNaPshot assay in 576 NSCLC...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Antineoplastic Combined Chemotherapy Protocols

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Non-Small-Cell Lung

Share to Follow-Up Studies

Share to Genes, Reporter

Share to MicroRNAs

Share to Patient Outcome Assessment

Share to RNA Interference

Source

Identifiers

PMID: 24997136
DOI: 10.1016/j.lungcan.2014.06.010

Genes

TYMS
MICA
FEN1
HDAC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MicroRNA-binding site SNPs in deregulated genes are associated with clinical outcome of non-small cell lung cancer.PMID 24997136Read ↗

A genetic polymorphism in pre-miR-27a confers clinical outcome of non-small cell lung cancer in a Chinese population.Semantic proximity Read ↗

MicroRNA-Related Genetic Variants Associated with Survival of Head and Neck Squamous Cell Carcinoma.Semantic proximity Read ↗

Polymorphisms in MicroRNAs are associated with survival in non-small cell lung cancer.Semantic proximity Read ↗

Variations within 3'-UTR of MDM4 gene contribute to clinical outcomes of advanced non-small cell lung cancer patients following platinum-based chemotherapy.Semantic proximity Read ↗

A genetic variation in microRNA target site of KRT81 gene is associated with survival in early-stage non-small-cell lung cancer.Semantic proximity Read ↗

Genetic variation in a microRNA-502 minding site in SET8 gene confers clinical outcome of non-small cell lung cancer in a Chinese population.Semantic proximity Read ↗

Potentially functional polymorphisms in DNA repair genes and non-small-cell lung cancer survival: a pathway-based analysis.Semantic proximity Read ↗

A polymorphism at the microRNA binding site in the 3' untranslated region of C14orf101 is associated with non-Hodgkin lymphoma overall survival.Semantic proximity Read ↗

Polymorphisms in MicroRNA Binding Sites Predict Colorectal Cancer Survival.Semantic proximity Read ↗

A genome-wide association study of survival in small-cell lung cancer patients treated with irinotecan plus cisplatin chemotherapy.Semantic proximity Read ↗

Association between polymorphisms in microRNA target sites and survival in early-stage non-small cell lung cancer.Semantic proximity Read ↗

MicroRNA-related genetic variants associated with clinical outcomes in early-stage non-small cell lung cancer patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.