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Article

A polymorphism at the microRNA binding site in the 3' untranslated region of C14orf101 is associated with non-Hodgkin lymphoma overall survival.

Cancer genetics - 1 Apr 2014

Yang Bo, Liu Chao, Diao Lanping, Wang Cuiju, Guo Zhanjun

Abstract excerpt

MicroRNAs (miRNAs) can bind to the 3' untranslated regions (UTRs) of messenger RNAs, where they interfere with translation and thereby regulate cell differentiation, apoptosis, and tumorigenesis. Genetic polymorphisms in the 3' UTRs targeted by miRNAs alter the strength of miRNA binding in a manner that affects the behavior of individual miRNAs. In this study, four miRNA binding-site single nucleotide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24831772
DOI: 10.1016/j.cancergen.2014.03.007

Genes

GOLGA7
RYR3

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