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Article

A genetic polymorphism in pre-miR-27a confers clinical outcome of non-small cell lung cancer in a Chinese population.

PloS one - 1 Jan 2013

Xu Jiali, Yin Zhiqiang, Shen Hong, Gao Wen, Qian Yingying, Pei Dong, Liu Lingxiang, Shu Yongqian

Abstract excerpt

BACKGROUND: Recent evidence indicates that microRNAs (miRNAs) can function as tumor suppressors and oncogenes. Single nucleotide polymorphisms (SNPs) at miRNA genes can influence the maturation of miRNAs or miRNA-mediated transcriptional regulation. Our objective was to investigate the association of SNPs in deregulated miRNAs with clinical outcome in patients with non-small cell lung cancer (NSCLC) in a Chinese...

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PMID: 24223174
DOI: 10.1371/journal.pone.0079135
PMCID: PMC3819265

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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