Article
Polymorphisms in MicroRNAs are associated with survival in non-small cell lung cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Nov 2014
Zhao Yang, Wei Qingyi, Hu Lingming, Chen Feng, Hu Zhibin, Heist Rebecca S, Su Li, Amos Christopher I, Shen Hongbing, Christiani David C
Abstract excerpt
BACKGROUND: MicroRNAs (miRNA) play important roles in the regulation of eukaryotic gene expression and are involved in human carcinogenesis. Single-nucleotide polymorphisms (SNP) in miRNA sequence may alter miRNA functions in gene regulation, which, in turn, may affect cancer risk and disease progression. METHODS: We conducted an analysis of associations of 142 miRNA SNPs with non-small cell lung cancer (NSCLC)...
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