Article
Association between polymorphisms in microRNA target sites and survival in early-stage non-small cell lung cancer.
Thoracic cancer - 1 Nov 2017
Yoo Seung Soo, Hong Mi Jeong, Lee Jang Hyuck, Choi Jin Eun, Lee Shin Yup, Lee Jaehee, Cha Seung Ick, Kim Chang Ho, Seok Yangki, Lee Eungbae, Cho Sukki, Jheon Sanghoon, Park Jae Yong
Abstract excerpt
A high-throughput mapping method of RNA-RNA interactions by crosslinking, ligation, and sequencing of hybrids (CLASH) can not only provide information about canonical but also non-canonical interactions. We evaluated the associations between variants in microRNA target sites using CLASH data and survival outcomes of 782 early-stage non-small cell lung cancer (NSCLC) patients who underwent curative surgical...
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