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Article

The effect of a single nucleotide polymorphism of the CYP4F2 gene on blood pressure and 20-hydroxyeicosatetraenoic acid excretion after weight loss.

Journal of hypertension - 1 Jul 2014

Ward Natalie C, Croft Kevin D, Puddey Ian B, Phillips Michael, van Bockxmeer Frank, Beilin Lawrence J, Barden Anne E

Abstract excerpt

BACKGROUND: Genetic background partly determines the efficacy of interventions to lower blood pressure (BP). The CYP4F2 and CYP4A11 enzymes are renal 20-hydroxyeicosatetraenoic acid (20-HETE) synthases that regulate BP. Gene variants of CYP4F2 and CYP4A11 associate with hypertension and stroke. W...

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Source

Identifiers

PMID: 24984178
DOI: 10.1097/HJH.0000000000000208

Genes

DBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24984178-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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The effect of a single nucleotide polymorphism of the CYP4F2 gene on blood pressure and 20-hydroxyeicosatetraenoic acid excretion after weight loss.PMID 24984178Read ↗

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